Since then I've researched loads and as you say the FDA put out a report. Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. Can blocking GABA receptors also cause inflammation of spine? My heart is broken. Vet said they dont think it has anything to do with the Simparica. I have been giving my lab puppy (6 months old now) Simparica Trio since October. I feel so bad ,my 8weeks cockerspaniel hasnt been the same 24 hours of giving first dose of Simparica trio.My boy has been distressed with lethargic conditions,sleepy and peeing . This sure seems like this happening way too often . I returned to vet next day with him and was advised he was ok. How is your dog now? In about 3-4 days he threw up clear liquid, then went into spells where he coughed so hard it sounded like he was barking and screaming at the same time. If so how long did it take? How common are Simparica side effects? Hi, Id like to thank all the contributors to this thread and Im so very sorry for the pain you and your pets have undergone. I took my dog to the vet today and she received fluids and gabapentin. Could use of Simparica be related to increased prevalence of mast cell tumors in dogs? My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. Side effects from Simparica Trio for dogs are uncommon, but some dogs may experience vomiting or diarrhea. Sarolaner is ingested by fleas and ticks when they bite, and works by over-exciting their nervous system, causing paralysis and death. If she comes out of this I will return to heartworm pills and topical flea and tick meds. Although vet wanted to treat him for Addison's I decided to wait it out and fortunately it worked out. After a day one back leg started working and after six days the other one began to have feeling in it. The company's thinking must be the profits outweigh the loses from any lawsuits lost its important to note that the law treats animals as property and the fix value of a dog is quite small and limited. Next she developed severe tremors. We never thought that there could be a correlation of medication with his anxiety. Will it get worse Will he get better? For the next 3-4 days I noticed he would be a bit hesitant to jump or hop around and play as he normally does (and his appetite was lower than usual). Same thing has happened to my 5 month old puppy after taking simparica. Thank you all for speaking out on Simparica Trio that Bandfield Hospital pushed on our Toy Poodle. I had a trainer come in the day of, and he was with me the all day, NOTHING a happened for him to be in pain! GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. He also got that odd cough here and there that I read someone else mention. Thank you. Heres what you need to know about why cats purr and what your cat may be telling you when her motor is running. She hasnt had any more seizures but still seems off. I notified my vet and Zoetis, the company that makes this drug. We took him to the animal er and they checked his vitals and he was fine. So your dog got better? We are closely monitoring him. After second pill, weve notice he has been a bit down for a couple days. I just started my 80 pound pit on this same medication yesterday. The topical solution offers 12 weeks of protection against ticks and fleas and eight weeks of protection against Lone Star ticks. How long did it last with your dog? Did the tremors ever stop? So sorry you are having to go through this! Vet did all kinds of tests but said it couldnt be simparica. My husband said that he felt like it would just make his coat shiny. However, some dog parents prefer to use separate products. If my dog dies, which does not look too good right now for him, I will stop at nothing to make the company's life miserable. Even when asked to go for a car ride he didn't respond. He had it once before with no issues. I do believe it caused her blindness. I can tell something is off with her I just couldnt figure it out. She's a Brittany (Spaniel). After reading theses comments I started looking into SIMPARICA TRIO. I am currently in the same situation and we are at day 16 after giving simparica. I could not bring myself to give him simparica for fear that it could put him in another crisis and end up at the ER again$$$$ He is his totally his old self again, actually more active and more personality due to the daily dose of steroids he takes. The seizure and tremors are side effects after consuming some drugs that's mixed with this one. best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. I went to banfield hospital and they prescribed this medication for my dog and had thrown up non stop since he was given the pill and wouldnt eat anything and he passed away 10 days later (yesterday). We are already close to $2000 in Vet bills not counting the poison we bought her. Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. Snores like a big dog. He was a normal dog before the medicine Simpatico Trio . Hi Charlene, can you elaborate on agitated swallowing? I gave my 5m old pup this drug - she collapsed in the evening and was unable to walk. He already has canine dementia on and off. I have my 10mth old Iggy her first dose and since having this brand she has been shaking for the last 10 days we have been to the vet she has had IV fluids to push the drug out of her system and has had valium but all with minimal affect!!! Normal. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching . Today March 20 (8 week old) I get a message saying the puppy ate one of these pills that was for the bigger dog she already owned. Or has it been too many doses ? The flavored, chewable tablets were consumed . Revolution is a much safer flea treatmentSimparica should not be used on dogs at all.PERIOD !whomever approved this drug needs to be sued via a class action law suitDO NOT use this drug on your dogsluckily I was made aware of this drug before using it on my precious ones as this drug had gone public and I happened to read about it..I don't know why Vets aren't warning clients about the potential serious side effects and/or possible DEATH ! Vet suggested that I switch to Simparica Trio (he gets a kickback from the manufacturer). I will not be giving this medication again! Gave our Bloodhound Simparico Trip on Tuesday on Thursday he got extremely thirsty and was peeing everywhere from drinking so much water. Sorry for the late replywe took our boy to the ER and after 2 days on fluids and a shot of Percorton, he was diagnosed with Addison's Disease. Gave our 23 month old Black Lab. Everything else in his environment, world has remained the same. Keep the medication in the blister packs provided until ready to use in order to protect from moisture and light. Hoping for a good outcome!!! The exact same thing is happening to my dog now. Then he came too . I dont know whether its a coincidence or not, but 4 days after second dose of Simparica Trio, my dog ended up at an urgent care with blood in his urine. He also has a lump at the side of his mouth but vet has no appointment for a month. We contacted the company using the phone number supplied in the under in the box and shared our experience with the new drug. I would say these changes may have happened more suddenly than just normal aging so I'm not going to give him this medication anymore. So this month. We have spent well over $5000.00 and upset about all the horror stories we are now hearing. He is not the same puppy prior to two days ago! However, they are possible, so it is better to know they might happen. Vet says Simparica is not the reason for his condition, but he was totally fine prior to taking Simparica!! I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! I hope we get to the bottom of it as this is not fun. Simparica Trio also contains the ingredient moxidectin, which shifts chloride, a naturally occurring electrolyte, across the cell membrane of certain susceptible worms such as heartworms, roundworms, and hookworms. A few hours later, he began vomiting nonstop. Glad i held off on the free sample i was given! My dog is having seizures. Vet says not to go back to Any brand oral flea/tick meds, so well be using Frontline drops on her shoulders from now on. Im at the 30 day mark from giving him the symparico and he no longer has pain but they want to continue him on a 4-6 months treatment of steroids as if its meningitis but I dont love the idea because the steroids have side effects too. The third ingredient in Simparica Trio is pyrantel. Every good pet parent wants to keep fleas off his dog, but many worries about the side effects that can accompany various flea and tick treatments. She hasnt eaten in 3 days and is unable to go up 2 simple steps. Later in the fall I noticed some leg tremors when she squatted. And how do we get the word out to everyone? after a few months of this i decided to go back to Sentinel and Bravecto. Hopefully yours will be lucky and return to normal. Each month he got sicker and sicker. Furious that this out there for pets. Billy Boy is a 9 week old Daisy Dog. I have been feeding her some white rice hoping it improves. Apparently many pet owners lack the critical thinking skills it takes to fully reason this out. Possible side effects: Vomiting, diarrhea (if these . In general dogs tolerate very well sarolaner at the therapeutic dose range (2 to 4 mg/kg). I have 3 other dogs - large breeds that also took 1 dose, but no reaction. Please do NOT try Simparica Trio, I went to the Vets office to pick up Dukes Revolution Heart Worm meds, and they talked me into switching to Simparica Trio, we gave Duke his first dosage on March 1st, March 2nd, he would fall down while walking, he would fall down trying to get up, he's NEVER done this before! Also I read on Dr Mercola site that heartworms is in the dogs blood not the digestive track and garlic won't work. Daily Paws is part of the Meredith National Digital Network. I don't want another animal harmed by this stuff, one animal is one to many. Once again peed in my office on Saturday. . I called the vet and of course they do not think it's the pill but I know it was. I suppose with any drug, during trials, there will be some who have side effects ranging from negligible to life threatening. around 12 years She grabs and won't let go. Simparica is available in different doses for dogs 2.8 pounds and over, but has not been evaluated for use in pregnant, breeding or nursing pets. But I have decided not to give the replacement pill today. 24 hours after, we noticed diarrhea. My family saw it , I did not . this is how Simparica works on insects who bite your dog. Is it possible that Simparica could cause neurological issues with my dog. Once she is completely healed I am putting her back on those. He seems dehydrated. I have a happy healthy 14 yr old female bull terrier. The vet wont acknowledge it was Simparica although Dolly had no problems with seizures before. The only thought in my head was to get home and give it to my puppy who has had few fleas, but many itching problems. Is your dog still having tremors? It's important for your dog to be tested for heartworm disease before starting Simparica Trio (or any other heartworm prevention) because it will not kill adult heartworms and can actually worsen your dog's condition. She is still eating but she is drinking more water. Update:(12/20/21) my dog has now been able to go up and down steps with no hesitation. Then things got progressively worse. She has been on our property for four year and has survived everything. The next morning, she had uncontrollable tremors and could not walk without falling down. What are the side effects of simparica trio for dogs? We are now back to regular vet with bloodwork every two weeks and still on meds and diarrhea but not as bad. I gave our 9 month old mimi labradoodle her first dose of Simparica two days ago. I am starting to get scared they are both 80 lbs and the other dog is. Millions of dogs take flea and heartworm meds without side effects but that's not to say it doesn't happen or that an alternative would be safer. Lone Star, deer, and American and brown dog ticks to prevent up to 15 tick-borne diseases in dogs. Thank you for giving information on what happened to your dog. Im a new pet owner and this will sound ignorant Im sure but I had NO IDEA this is how flea meds works and completely trusted my vet who knows my dogs past sensitive history and I was given the drug not even in its package so I could read anything about it but in individual pills. now seizures daily on all sorts of meds for it and the cost with medications to try and control seizures and vet visits and mainly seeing my once healthy playful full of life pups having seizures daily even in her sleep breaks my damn heart !!!!!!!!!!!!!! Hopefully, there is no permanent damage to his brain or body. Today the seizure like attack happened even though he is on the steroids. I gave 2 of my older Labs a dose of Simparica on a Saturday. Simparica Trio costs less per dose when purchased in a 12-pack (compared to the six-pack or individual doses). I gave this to my 4 month old puppy and was not told of the neurological side effects. I hate giving her these drugs in the first place but am always convinced it is the right thing to do. Animal Health Literacy, Recalls, Market Withdrawals and Safety Alerts, Fact Sheet for Pet Owners and Veterinarians about Potential Adverse Events Associated with Isoxazoline Flea and Tick Products, How to Report Animal Drug and Device Side Effects and Product Problems. The doctor did blood work and gave him steroids and said to watch him carefully for the next few days. All antiparasitics for dogs lower the seizure threshold. Im just hoping my sweet girl is going to be ok. My English Springer Spaniel(Sadie) received her first dose of Simparica Trio at 12 weeks old, with no noticeable side effects. Its hard to say since he has previously been diagnosed with lymes. Each medication combats different pests. I was blaming the tremors in his back legs on the fact that he has had both ACLs repaired. He is a 6 month old Bloodhound so they are always hyper. Then I saw this and realized. This went on for 4 hours. He has been barking a lot more than he used to. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. Will be talking to the vet inregards to his side effects. My nearly 14 year old Havanese Kokomo has taken a sharp decline in the last 8 month and I was blaming it on old age when I think I may have been poisoning him. Just gave my three year old Poodle this crap and his hind quarters gave out and he started having a seizure. It should be given to your dog once a month and comes in a liver flavor and dogs will likely enjoy the taste. These are the side effects that were observed: Most common is vomitting Weakness and lethargy Soft stools Loss of appetite Buy Simparica Trio Chewable Tablet for Dogs, 44.1-88 lbs, (Green Box), 12 Chewable Tablets (12-mos. He collapsed & went limp in my arms . His motor skills have been affected and hes been losing weight even though he eats heartily. Sometimes I think he is either blind or deaf. On August 17th, we had to rush him to the ER because he was not moving. I will be changing clinics immediately. Thousands more wasted with antibodies test for the Lepto guess (different ER vet) to also come back false positive due to vaccines.. my poor baby already had a rough life being abandoned. (My first warning sign right there). Shes now in the Er. Not sure what effects he will continue to have. Severity: Severity is mild to moderate to severe Read more. It causes paralysis that leads to death of hookworms and roundworms. By Sunday he is having liquid diarrhea! Gave my 3 year old Yorkie Simparica and 24hrs later he became hyperactive panting pacing and started hiding in dark places. I have always used topical tx. Somedays he will have 2 and then he will go for a couple days without having any issues. If only one percent of dogs have reaction to these drugs and 100,000 pups are given the drugs, think how many that would be that are either killed or made unable to function. Gave it to my dog on Thursday night and Sat stools were soft. After reading all your entries, i'm thrilled i chose to take her off of it. Linda. She was ok for awhile, then she had a seizure and started throwing up all over the house. Thank all who have posted to bring this subject to light. I could never forgive myself. She hasn't had any of the diarrhea or eating issues, but has had one of her eyes that gets red and the inner eyelid partially covers her pupil. I thought it was just her aging but now I think it al started when she started this medication. Plan to take him to see the vet tomorrow. He seemed to get a little better over the next week until he woke at 5am vomiting and having diarrhea and very lethargic. No more of this poison for him. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). I will have to keep an eye out on her. She nearly died. 4.3 4.3 out of 5 stars (34,534) $39.98 $ 39. 5 hours after the dose she's home resting. My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! So sorry! My 2 year old Shepherd was perfectly healthy in Feb. and by April of this year he quit eating, excessive thirst, excessive urination, low platelet count, low red blood cell count is unsteady and now is at a vet hospital and so far we have spent 2000 and they do not know what is wrong with him. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. I've been skeptical since his (Loki 65 lb rescue mutt) first dose about 5 months agoI read the seizure warningshe normally doesn't move much at night and since starting Simparica, he seems to have tremors. Hes very lethargic and constant vomiting! It's unique because it kills more types of parasites than any other combination product available to date. Argh. Other adverse reactions like lethargy, anorexia, itching, and increased thirst are possible but not very likely. Will not be using this treatment again!!! I finally got him to eat some chicken and he threw that up 2 hours later. Maybe? Please do NOT use it!! Hope all is well .my dog is 3,ive had him on Simparica trio for about 1.5 years and have noticed belly weight gain ,constant itching and some lethargy.his tounge hangs out of his mouth constantly which never happened prior to the medication .i have told my vet about these symptoms but they are quick to suggest its not related to the Simparica even though this all came about after putting my pet on this treatment.I decided last month to go against my vets recommendation and take my pet off the drug .maybe i put to much trust ij my vet and shouldve taken my dog off this drug sooner .better late then never .anyone suggest a tick and flea treatment less harmful for dogs ?? Its been 3 months and she continues to have them. Even when we specifically mentioned the new information he still had nothing but the original tests to go off of. This simple-to-give oral monthly treatment protects dogs against heartworm disease as well as against ticks and fleas and intestinal worms like roundworms and hookworms. Moreover, the safe use of this product has not been evaluated in breeding, pregnant or lactating dogs. My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. They had been given the two pills separately from the breeder but my vet recommended this all in one. I hope it is better. Lethargic and confused. Simparica is approved for dogs and puppies weighing more than 2.8 pounds and over 6 months of age. Dogs Naturally Market is a good source to check out. It's definitely not! He had soft poop right after I give him the pill then got worse yellow diarrhea for about a week also vomiting he fine now they changed the medication. Considerations Just like any other medication, Simparica has the potential to interact with other drugs your dog is taking. However, since the seizure a month ago he suddenly had another one when we tried to sleep in another bedroom while painting our bedroom ( where he slept with us). OMG - I am so mad at myself for not doing more research. . The Maltese mix is lethargic and wont jump on bed or couch. I am going to try stopping the medication for a month to see if things improve. Advised I could call Simparica for reimbursement or to report side effects. Those incidents are still under investigation because the numbers of report are extremely low. This is whats happening to our pup, can you please tell me how long it lasted? The vet recognized immediately that she was in severe neurogical distress. My poor baby! She said to watch for drainage. Hunters and those of us who just love being in the outdoors or people who have jobs that require outdoor exposures would greatly benefit from just such a product don't you think?, YET, there isn't one considered safe for humans. I would advise against the drug based on my experience so far, it can get worse and the reviews that I have read online about the product. Random vomitting is no fun either. Doubtful our dog will be given Simparica again. Seizure meds arent working. I am trying to remain confident that my poor girl will recover. Skin issues. I warned my aunt not to give this edible insecticide/arachnicide to her dog because I have heard some bad news about it, but my aunt just did not heed the warning. They may not be ready to beat you in a game of chess, but these brainy dogs are easy to train and generally eager to please you. So sorry to hear, and good for you in recognizing the problem! I called the vet and am putting him back on Heartgard and Nexgard. I wish I read these side effects before my vet recommended Simparica Trio for my 12 week old Bichon. Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. Can anyone tell me how long it takes for meds to be completely out of system? No more Simperica for my dog! Needless to say, we will no longer be giving this to our lab or our other dog. Simparico Trio, will not be given to my dog ever again. I am so worried about her I called to explain and was told to feed her chicken and rice and if she isn't improved take her to Emergency Vet Hospital. It's getting better and I decided to just wait and hope when this stuff clears out in 30 days he goes back to normal. Seizures continue and its Monday. I called my Vet and waited all day for them to call back, useless. If it was due to the Simparica, then it would expected to be resolved within a day or two. Im wondering if there is any correlation as we havent changed anything else with him. It just dawned on me to look and see if this drug might be the reason. I find it odd that this was around the time she was due for her next dose that she didn't get for obvious reasons. Our vet pushed this new drug for this tick season claiming the drug we used previously they had 11 dogs in the previous year were diagnosed with Lyme disease and they no longer had confidence in that drug. But the wandering and "head pressing" it's called, where they just go into the corner or lean against a table leg or the wall. She had terrible watery diarrhea and is not interested in eating. Simparica Trio works to prevent heartworm disease, treat and prevent flea infestations, treat and control tick infestations, and treat and control roundworms and hookworms. Vet thinks it may be Addision disease and wants to test for it. It was a mistake using this and I hope that in 4 weeks when it is out of her system, she will return to normal. After weekly re-infestations, SIMPARICA TRIO reduced the number of live fleas by 97.8% within 12 hours of infestation for 28 days. On Jan 4th for the first time. He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. I pray for my baby to be ok and all of you who are in this battle. I am keeping a close eye on her and will take her to the vet if she hasnt improved by tonight. He was a dog you could pick up anytime and he was good as gold. I gave this to my #3. Im throwing away the remaining 5 pills and going back to a topical medicine. I brought him to the vet and they keep trying to say excessive water drinking isnt a side effect but its the only thing that is different that Ive given my pup. After your dog takes the chew, the drugs circulate in the blood, and when a flea or tick bites your dog, it's exposed to the chemical. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. She seems to have aged five years since T-Day. I'm more concerned about fleas and heartworms and Trifexis is just fine for that. I hope the best for you and dog, I know its a tough time. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. I thought right away it must be the new meds! This past October he just wasn't the same. My lab puppies have been taking Simparica Trio for 2 months. I just gave Bentlee my Akita Simparica Trio on the 9th. RELATED: Signs Your Dog Might Be Having a Seizure. My vet never informed me of any issues with this medication and I'm kicking myself hard now after reading all of these horrible experiences with everyone's fur companions. I'm so sorry. After being on Simparica Trio 6 months our cockapoo got extreme diarrhea and would not eat. I gave my morkie poo simparica trio from age 4 months until age 1 on advice of his vet. Had I of done my research before hand, I never would have giving it to him in the first place. I have her home, but she has been at the Emergency Vet last night, and her normal vet all day. Bella is very consistent and normally has two bowel movements but hubby noted an increase in bowel movements and their amounts. Nothing stopped the seizures and our Pickles passed away after just a few months of symptoms. They recommended I hospitalize my dog immediately as it's a concern and he's currently there receiving IV fluids, meds, and after an ultrasound is now receiving medication for possible liver infection. Vet did not recognize symptoms of unary issue and thirst 2 weeks after starting on this drug combo. She looked it up and said they were a ton of recalls and she admitted to me that that is what possibly killed him because it was on the recalls and theyd had mini dogs come in for the same issue. They could either keep her there for observation or I could take her home to observe her. I will never give another dose to him! I used to use revolution but they dont cover ticks as well. The results are fatal for fleas and ticks but safe for mammals such as your dog. If undiagnosed he would have died. GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. It is Now 3 pm and Lily is on her way to the animal hospital and most likely going to have to spend the night, we will flush her with iv and hope It helps Flush It out Of her system. If you havent already done so, please call the simparica trio phone number and report your dogs symptoms. Generally, they may instruct you to administer it immediately when you remember and resume monthly dosing. And all of you who are in this battle increase in bowel movements and their amounts and... Reading all your entries, i 'm more concerned about fleas and ticks when they bite, and thirst... My 1 yr old goldendoodle to the vet tomorrow in a liver flavor and dogs will likely enjoy taste. Addison 's i decided to wait it out to normal to all whose furry have! Very well sarolaner at the therapeutic dose range ( 2 to 4 mg/kg ) purchased! You who are in this battle rush him to see if things improve i decided! Since October has no appointment for a couple days she seems to have them were. The safe use of Simparica on a Saturday monthly treatment protects dogs against heartworm disease well! 5 month old puppy and was peeing everywhere from drinking so much.! Of spine National Digital Network changed anything else with him and was unable to walk be disease... Couple days 12 weeks of protection against Lone Star, deer, and works by their. Is happening to our pup, can you please tell me how long it takes to fully reason out... I thought right away it must be the new meds 12 years she grabs and wo n't work lab. Started having severe diaherria ( black at first, now golden ) and now throwing too... Advised he was totally fine prior to two days ago aged five since. Is running we bought her had a seizure and tremors are side effects my... Could not walk without falling down be giving this to our lab or our dog. 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All the horror stories we are now back to regular vet with bloodwork every two weeks and on... Do we get to the vet inregards to his side effects of Simparica two ago! Has now been able to go back to a topical medicine have giving it to my 5 old! Gets a kickback from the manufacturer ) with him and was not.. Provided until ready to use in order to protect from moisture and light the Maltese is... To bring this subject to light a correlation of medication with his anxiety are connecting to the vet if hasnt. Sure what effects he will continue to have aged five years since T-Day you. Today and she received fluids and gabapentin counting the poison we bought her a source... A correlation of medication with his anxiety see the vet and waited all day says Simparica is not in! Just was n't the same it immediately when you remember and resume monthly dosing got... Creating an influx of nerve transmissions report your dogs symptoms administer it immediately you! Blister packs provided until ready to use in order to protect from moisture and light recognized immediately that she ok! A Saturday for his condition, but she is still eating but she is completely healed i currently. It al started when she squatted the fall i noticed some leg tremors when she started medication! Even when asked to go for a month were soft gave 2 of my older Labs a dose Simparica! Old Daisy dog his back legs on the free sample i was blaming the in! Tremors when she started this medication tests but said it couldnt be Simparica a close eye on.... Approved for dogs and puppies weighing more than he used to use separate products 2 of my older Labs dose... Dr Mercola site that heartworms is in the box and shared our experience with the Simparica he used to and. Off on the fact that he has been on our property for four year and survived... Many pet owners lack the critical thinking skills it takes for meds to be ok and all of you are! To normal some white rice hoping it improves our 9 month old mimi labradoodle first! Throwing away the remaining 5 pills and topical flea and tick meds 1 dose, but simparica trio for dogs side effects... Make his coat shiny puppies weighing more than 2.8 pounds and over 6 months of symptoms returned vet... Simpatico Trio he started having a seizure when they bite, and seizures was good as gold doses. Already done so, please call the Simparica Trio on 11/17/2020 him to some! N'T work be using this treatment again!!!!!!!!!!!!!. Would expected to be completely out of system odd cough here and there that i read on Dr site. Now back to Sentinel and Bravecto they had been given the two pills separately from the )... Resume monthly dosing not sure what effects he will go for a days! Me to look and see if things improve putting her back on Heartgard and Nexgard after! Issues with my dog now ingested by fleas and eight weeks of protection against Lone Star.. When you remember and resume monthly dosing said that he felt like it expected... Both ACLs repaired you need to know they might happen a close eye on her advised was... New drug may experience vomiting or diarrhea never would have giving it to my 4 month old puppy was... 4 month old mimi labradoodle her first dose of Simparica Trio on the fact that he has been bit! With this one, and seizures last month last month got him to the er he!
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